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Translating old drugs into new treatments: ribosomal frameshifting as a target for antiviral agents
Programmed ribosomal frameshifting is used by many viruses to regulate the production of structural and enzymatic proteins. Altering the frameshifting efficiencies disrupts the virus life cycle and eliminates or reduces virus production. Ribosomal frameshifting therefore provides a unique target on...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science Ltd.
1998
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7127214/ https://www.ncbi.nlm.nih.gov/pubmed/9586242 http://dx.doi.org/10.1016/S0167-7799(97)01167-0 |