Cargando…

Translating old drugs into new treatments: ribosomal frameshifting as a target for antiviral agents

Programmed ribosomal frameshifting is used by many viruses to regulate the production of structural and enzymatic proteins. Altering the frameshifting efficiencies disrupts the virus life cycle and eliminates or reduces virus production. Ribosomal frameshifting therefore provides a unique target on...

Descripción completa

Detalles Bibliográficos
Autores principales: Dinman, Jonathan D, Ruiz-Echevarria, Maria J, Peltz, Stuart W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Ltd. 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7127214/
https://www.ncbi.nlm.nih.gov/pubmed/9586242
http://dx.doi.org/10.1016/S0167-7799(97)01167-0