Apoptosis induced by a cytopathic hepatitis A virus is dependent on caspase activation following ribosomal RNA degradation but occurs in the absence of 2′–5′ oligoadenylate synthetase

We have presented previously evidence that the cytopathogenic 18f strain of hepatitis A virus (HAV) induced degradation of ribosomal RNA (rRNA) in infected cells [Arch. Virol. 148 (2003) 1275–1300]. In contrast, the non-cytopathogenic parent virus HM175 clone 1 had no effect on rRNA integrity. We pr...

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Detalles Bibliográficos
Autores principales: Goswami, Biswendu B., Kulka, Michael, Ngo, Diana, Cebula, Thomas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2004
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7127220/
https://www.ncbi.nlm.nih.gov/pubmed/15451183
http://dx.doi.org/10.1016/j.antiviral.2004.02.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7127220/
https://www.ncbi.nlm.nih.gov/pubmed/15451183
http://dx.doi.org/10.1016/j.antiviral.2004.02.004

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