High-affinity Na(+)-dependent dicarboxylate cotransporter promotes cellular senescence by inhibiting SIRT1

High-affinity Na(+)-dependent dicarboxylate cotransporter (NaDC3) can transport Krebs cycle intermediates into cells. Our previous study has shown that NaDC3 promotes cellular senescence, but its mechanism is not clear. It is known that when the concentration of intermediates in Krebs cycle is incre...

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Detalles Bibliográficos
Autores principales: Liu, Weiping, Hong, Quan, Bai, Xue-Yuan, Fu, Bo, Xie, Yuansheng, Zhang, Xueguang, Li, Jianjun, Shi, Suozhu, Lv, Yang, Sun, Xuefeng, Chen, Xiangmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ireland Ltd. 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7127227/
https://www.ncbi.nlm.nih.gov/pubmed/20813124
http://dx.doi.org/10.1016/j.mad.2010.08.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7127227/
https://www.ncbi.nlm.nih.gov/pubmed/20813124
http://dx.doi.org/10.1016/j.mad.2010.08.006

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