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Evaluation of a PCR-electrospray ionization mass spectrometry platform for detection and identification of fungal pathogens directly from prospectively collected bronchoalveolar lavage specimens

The incidence of invasive fungal infections is on the rise worldwide due to the growth of the immunocompromised population. We report here the use of a diagnostic assay that utilizes a universal extraction method, broad spectrum PCR amplification and analysis via electrospray ionization mass spectro...

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Detalles Bibliográficos
Autores principales: Jia, Bei, Lovari, Robert, Miller, Heather, Metzgar, David, Massire, Christian, Carolan, Heather, Toleno, Donna, D'Alessio, Franco, Rothman, Richard, Blyn, Lawrence B., Zhang, Sean X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7127232/
https://www.ncbi.nlm.nih.gov/pubmed/32107092
http://dx.doi.org/10.1016/j.diagmicrobio.2020.114988