One time intranasal vaccination with a modified vaccinia Tiantan strain MVTT(ZCI) protects animals against pathogenic viral challenge

To combat variola virus in bioterrorist attacks, it is desirable to develop a noninvasive vaccine. Based on the vaccinia Tiantan (VTT) strain, which was historically used to eradicate the smallpox in China, we generated a modified VTT (MVTT(ZCI)) by removing the hemagglutinin gene and an 11,944 bp g...

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Detalles Bibliográficos
Autores principales: Yu, Wenbo, Fang, Qing, Zhu, Weijun, Wang, Haibo, Tien, Po, Zhang, Linqi, Chen, Zhiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7127290/
https://www.ncbi.nlm.nih.gov/pubmed/20045097
http://dx.doi.org/10.1016/j.vaccine.2009.12.038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7127290/
https://www.ncbi.nlm.nih.gov/pubmed/20045097
http://dx.doi.org/10.1016/j.vaccine.2009.12.038

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