Synthesis and anti-HIV studies of 2- and 3-adamantyl-substituted thiazolidin-4-ones

A series of novel thiazolidin-4-ones bearing a lipophilic adamantyl substituent at position 2 or 3 were synthesized. A majority of them showed a modest anti-HIV-1 activity, whereas 2-adamantan-1-yl-3-(4,6-dimethylpyrimidin-2-yl)-thiazolidin-4-one (8) was endowed with a remarkable antiviral potency (...

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Detalles Bibliográficos
Autores principales: Balzarini, Jan, Orzeszko-Krzesińska, Barbara, Maurin, Jan K., Orzeszko, Andrzej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Masson SAS. 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7127420/
https://www.ncbi.nlm.nih.gov/pubmed/18420310
http://dx.doi.org/10.1016/j.ejmech.2008.02.039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7127420/
https://www.ncbi.nlm.nih.gov/pubmed/18420310
http://dx.doi.org/10.1016/j.ejmech.2008.02.039

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