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Molecular drug-organiser: Synthesis, characterization and biological evaluation of penicillin V and/or nalidixic acid calixarene-based podands

Two well-known antibiotic heterocycles, the ‘quinolone’ nalidixic acid and the β-lactam penicillin V, active at different levels of the bacterial growth process, have been attached via an ether–ester junction to the p-tert-butylcalix[4]arene lower rim, in alternate position. The resulting hydrophobi...

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Detalles Bibliográficos
Autores principales: Ben Salem, Adel, Sautrey, Guillaume, Fontanay, Stéphane, Duval, Raphaël E., Regnouf-de-Vains, Jean-Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7127436/
https://www.ncbi.nlm.nih.gov/pubmed/22075235
http://dx.doi.org/10.1016/j.bmc.2011.10.031