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Molecular drug-organiser: Synthesis, characterization and biological evaluation of penicillin V and/or nalidixic acid calixarene-based podands
Two well-known antibiotic heterocycles, the ‘quinolone’ nalidixic acid and the β-lactam penicillin V, active at different levels of the bacterial growth process, have been attached via an ether–ester junction to the p-tert-butylcalix[4]arene lower rim, in alternate position. The resulting hydrophobi...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd.
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7127436/ https://www.ncbi.nlm.nih.gov/pubmed/22075235 http://dx.doi.org/10.1016/j.bmc.2011.10.031 |