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Development and efficacy of a novel live-attenuated QX-like nephropathogenic infectious bronchitis virus vaccine in China

In this study, we attenuated a Chinese QX-like nephropathogenic infectious bronchitis virus (IBV) strain, YX10, by passaging through fertilized chicken eggs. The 90th passage strain (YX10p90) was selected as the live-attenuated vaccine candidate strain. YX10p90 was found to be safe in 7-day-old spec...

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Detalles Bibliográficos
Autores principales: Feng, Keyu, Xue, Yu, Wang, Jinglan, Chen, Weiguo, Chen, Feng, Bi, Yingzuo, Xie, Qingmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7127481/
https://www.ncbi.nlm.nih.gov/pubmed/25636916
http://dx.doi.org/10.1016/j.vaccine.2015.01.036