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Attenuation of SARS coronavirus by a short hairpin RNA expression plasmid targeting RNA-dependent RNA polymerase()

Severe acute respiratory syndrome (SARS) is a highly contagious and sometimes a lethal disease, which spread over five continents in 2002–2003. Laboratory analysis showed that the etiologic agent for SARS is a new type of coronavirus. Currently, there is no specific treatment for this disease. RNA i...

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Detalles Bibliográficos
Autores principales: Lu, Aili, Zhang, Huanqing, Zhang, Xiaoyan, Wang, Hongxia, Hu, Qikuan, Shen, Li, Schaffhausen, Brian S., Hou, Weimin, Li, Linsong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7127537/
https://www.ncbi.nlm.nih.gov/pubmed/15183056
http://dx.doi.org/10.1016/j.virol.2004.03.031