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NS5B induces up-regulation of the BH3-only protein, BIK, essential for the hepatitis C virus RNA replication and viral release

Hepatitis C virus (HCV) induces cytopathic effects in the form of hepatocytes apoptosis thought to be resulted from the interaction between viral proteins and host factors. Using pathway specific PCR array, we identified 9 apoptosis-related genes that are dysregulated during HCV infection, of which...

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Detalles Bibliográficos
Autores principales: Aweya, Jude Juventus, Sze, Ching Wooen, Bayega, Anthony, Mohd-Ismail, Nur Khairiah, Deng, Lin, Hotta, Hak, Tan, Yee-Joo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7127593/
https://www.ncbi.nlm.nih.gov/pubmed/25463603
http://dx.doi.org/10.1016/j.virol.2014.10.027