Molecular docking identifies the binding of 3-chloropyridine moieties specifically to the S1 pocket of SARS-CoV M(pro)

The 3C-like main proteinase of the severe acute respiratory syndrome (SARS) coronavirus, SARS-CoV M(pro), is widely considered to be a major drug target for the development of anti-SARS treatment. Based on the chemical structure of a lead compound from a previous screening, we have designed and synt...

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Detalles Bibliográficos
Autores principales: Niu, Chunying, Yin, Jiang, Zhang, Jianmin, Vederas, John C., James, Michael N.G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7127602/
https://www.ncbi.nlm.nih.gov/pubmed/17931870
http://dx.doi.org/10.1016/j.bmc.2007.09.034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7127602/
https://www.ncbi.nlm.nih.gov/pubmed/17931870
http://dx.doi.org/10.1016/j.bmc.2007.09.034

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