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Molecular docking identifies the binding of 3-chloropyridine moieties specifically to the S1 pocket of SARS-CoV M(pro)
The 3C-like main proteinase of the severe acute respiratory syndrome (SARS) coronavirus, SARS-CoV M(pro), is widely considered to be a major drug target for the development of anti-SARS treatment. Based on the chemical structure of a lead compound from a previous screening, we have designed and synt...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier Ltd.
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7127602/ https://www.ncbi.nlm.nih.gov/pubmed/17931870 http://dx.doi.org/10.1016/j.bmc.2007.09.034 |