1-[2-(2-Benzoyl- and 2-benzylphenoxy)ethyl]uracils as potent anti-HIV-1 agents

Non-nucleoside reverse transcriptase inhibitors (NNRTI) are key components in highly active antiretroviral therapy for treating HIV-1. Herein we present the synthesis for a series of N1-alkylated uracil derivatives bearing ω-(2-benzyl- and 2-benzoylphenoxy)alkyl substituents as novel NNRTIs. These c...

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Detalles Bibliográficos
Autores principales: Novikov, Mikhail S., Ivanova, Olga N., Ivanov, Alexander V., Ozerov, Alexander A., Valuev-Elliston, Vladimir T., Temburnikar, Kartik, Gurskaya, Galina V., Kochetkov, Sergey N., Pannecouque, Christophe, Balzarini, Jan, Seley-Radtke, Katherine L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7127633/
https://www.ncbi.nlm.nih.gov/pubmed/21903401
http://dx.doi.org/10.1016/j.bmc.2011.08.025

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7127633/
https://www.ncbi.nlm.nih.gov/pubmed/21903401
http://dx.doi.org/10.1016/j.bmc.2011.08.025

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