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Effector CD8(+) T cell-derived interleukin-10 enhances acute liver immunopathology

BACKGROUND & AIMS: Besides secreting pro-inflammatory cytokines, chemokines and effector molecules, effector CD8(+) T cells that arise upon acute infection with certain viruses have been shown to produce the regulatory cytokine interleukin (IL)-10 and, therefore, contain immunopathology. Whether...

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Detalles Bibliográficos
Autores principales: Fioravanti, Jessica, Di Lucia, Pietro, Magini, Diletta, Moalli, Federica, Boni, Carolina, Benechet, Alexandre Pierre, Fumagalli, Valeria, Inverso, Donato, Vecchi, Andrea, Fiocchi, Amleto, Wieland, Stefan, Purcell, Robert, Ferrari, Carlo, Chisari, Francis V., Guidotti, Luca G., Iannacone, Matteo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Association for the Study of the Liver. Published by Elsevier B.V. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7127652/
https://www.ncbi.nlm.nih.gov/pubmed/28483675
http://dx.doi.org/10.1016/j.jhep.2017.04.020