Design, synthesis, antiviral and cytostatic activity of ω-(1H-1,2,3-triazol-1-yl)(polyhydroxy)alkylphosphonates as acyclic nucleotide analogues

The efficient synthesis of a new series of polyhydroxylated dibenzyl ω-(1H-1,2,3-triazol-1-yl)alkylphosphonates as acyclic nucleotide analogues is described starting from dibenzyl ω-azido(polyhydroxy)alkylphosphonates and selected alkynes under microwave irradiation. Selected O,O-dibenzylphosphonate...

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Detalles Bibliográficos
Autores principales: Głowacka, Iwona E., Balzarini, Jan, Andrei, Graciela, Snoeck, Robert, Schols, Dominique, Piotrowska, Dorota G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7127666/
https://www.ncbi.nlm.nih.gov/pubmed/24906510
http://dx.doi.org/10.1016/j.bmc.2014.05.020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7127666/
https://www.ncbi.nlm.nih.gov/pubmed/24906510
http://dx.doi.org/10.1016/j.bmc.2014.05.020

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