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Molecular mechanisms of the secretion of cytokines and chemokines from human monocytes activated by pneumococcal surface protein A (PspA): Roles of mitogen-activated protein kinases and NF-kappaB

Pneumococcal surface protein A (PspA) plays a key role in the pathogenesis of invasive pneumococcal infection. PspA might modulate specific immune responses in human population. Circulating monocytes are essential for the innate responses and subsequent acquired immune responses to Streptococcus pne...

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Detalles Bibliográficos
Autores principales: Cao, Ju, Chen, Tingmei, Gong, Yi, Ying, Bingwu, Li, Dairong, Xu, Wenchun, Zhang, Xuemei, Wang, Lanlan, Yin, Yibing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7127760/
https://www.ncbi.nlm.nih.gov/pubmed/20227479
http://dx.doi.org/10.1016/j.micpath.2010.03.001