Cargando…

Synthesis and antiviral evaluation of acyclic azanucleosides developed from sulfanilamide as a lead structure

The acyclic azanucleosides with 2-, 3-, or 4-aminobenzenesulfonyl function at the nitrogen atom of the sugar mimic were prepared by coupling of 2-, 3-, or 4-nitro-N-(2-pivaloyloxyethyl)-N-(pivaloyloxymethyl)benzenesulfonamide with the silylated pyrimidine nucleobases followed by the reduction of the...

Descripción completa

Detalles Bibliográficos
Autores principales: Gawin, Rafał, De Clercq, Erik, Naesens, Lieve, Koszytkowska-Stawińska, Mariola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7127773/
https://www.ncbi.nlm.nih.gov/pubmed/18778942
http://dx.doi.org/10.1016/j.bmc.2008.08.041