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Preparation, Characterization, and in vivo Evaluation of NK4-Conjugated Hydroxycamptothecin-Loaded Liposomes

PURPOSE: In this study, NK4-conjugated hydroxycamptothecin liposomes (NK4-HCPT-Lips) were prepared with the aim of improving drug targeting to the liver. METHODS: NK4-HCPT-Lips were prepared using the thin-film dispersion method. In vitro antitumor activities were evaluated by MTT assay. HCPT levels...

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Detalles Bibliográficos
Autores principales: Zhou, Ting, Zhang, Wei, Cheng, Dongliang, Tang, Xin, Feng, Jianfang, Wu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7127779/
https://www.ncbi.nlm.nih.gov/pubmed/32280220
http://dx.doi.org/10.2147/IJN.S243746