Synthesis and in vitro antiviral evaluation of 4-substituted 3,4-dihydropyrimidinones

A series of 4-substituted 3,4-dihydropyrimidine-2-ones (DHPM) was synthesized, characterized by IR, (1)H NMR, (13)C NMR and HRMS spectra. The compounds were evaluated in vitro for their antiviral activity against a broad range of DNA and RNA viruses, along with assessment for potential cytotoxicity...

Descripción completa

Detalles Bibliográficos
Autores principales: Kumarasamy, Dhanabal, Roy, Biswajit Gopal, Rocha-Pereira, Joana, Neyts, Johan, Nanjappan, Satheeshkumar, Maity, Subhasis, Mookerjee, Musfiqua, Naesens, Lieve
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7127791/
https://www.ncbi.nlm.nih.gov/pubmed/27979594
http://dx.doi.org/10.1016/j.bmcl.2016.12.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7127791/
https://www.ncbi.nlm.nih.gov/pubmed/27979594
http://dx.doi.org/10.1016/j.bmcl.2016.12.010

Ejemplares similares