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Glycyrrhizic acid derivatives as influenza A/H1N1 virus inhibitors

This Letter describes the synthesis and antiviral activity study of some glycyrrhizic acid (GL) derivatives against influenza A/H1N1/pdm09 virus in MDCK cells. Conjugation of GL with l-amino acids or their methyl esters, and amino sugar (d-galactose amine) dramatically changed its activity. The most...

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Detalles Bibliográficos
Autores principales: Baltina, Lidia A., Zarubaev, Vladimir V., Baltina, Lia A., Orshanskaya, Iana A., Fairushina, Alina I., Kiselev, Oleg I., Yunusov, Marat S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7127794/
https://www.ncbi.nlm.nih.gov/pubmed/25801933
http://dx.doi.org/10.1016/j.bmcl.2015.02.074