Design, synthesis, and biological evaluation of novel iso-d-2′,3′-dideoxy-3′-fluorothianucleoside derivatives

Novel iso-d-2′,3′-dideoxythianucleoside derivatives 1–4 were designed and asymmetrically synthesized as a bioisostere of lamivudine to search for new anti-HIV agents. The information about using sulfur participation occurred on DAST fluorination and Mitsunobu reaction will be of great help in synthe...

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Detalles Bibliográficos
Autores principales: Kim, Kyung Ran, Moon, Hyung Ryong, Park, Ah-Young, Chun, Moon Woo, Jeong, Lak Shin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2007
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7127805/
https://www.ncbi.nlm.nih.gov/pubmed/17046264
http://dx.doi.org/10.1016/j.bmc.2006.09.066

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7127805/
https://www.ncbi.nlm.nih.gov/pubmed/17046264
http://dx.doi.org/10.1016/j.bmc.2006.09.066

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