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Proniosomal Telmisartan Tablets: Formulation, in vitro Evaluation and in vivo Comparative Pharmacokinetic Study in Rabbits

OBJECTIVE: The purpose of this study was to prepare proniosomal vesicles of Telmisartan (TEL) to be compressed into tablets which will be further evaluated in vitro and in vivo. MATERIALS AND METHODS: An experimental design was adopted using surfactants of different HLB values (span 40-brij 35), dif...

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Detalles Bibliográficos
Autores principales: Teaima, Mahmoud Hasan, Yasser, Mohamed, El-Nabarawi, Mohamed Ahmed, Helal, Doaa Ahmed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7127815/
https://www.ncbi.nlm.nih.gov/pubmed/32280201
http://dx.doi.org/10.2147/DDDT.S245013