Viral RNAs: Lessons from the Enemy
Viruses are adept at evolving or co-opting genomic elements that allow them to maximize their replication potential in the infected host. This evolutionary plasticity makes viruses an invaluable system to identify new mechanisms used not only by viruses but also by vertebrate cells to modulate gene...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Elsevier Inc.
2009
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7127818/ https://www.ncbi.nlm.nih.gov/pubmed/19239880 http://dx.doi.org/10.1016/j.cell.2009.01.048 |
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author | Cullen, Bryan R. |
author_facet | Cullen, Bryan R. |
author_sort | Cullen, Bryan R. |
collection | PubMed |
description | Viruses are adept at evolving or co-opting genomic elements that allow them to maximize their replication potential in the infected host. This evolutionary plasticity makes viruses an invaluable system to identify new mechanisms used not only by viruses but also by vertebrate cells to modulate gene expression. Here, I discuss the identification and characterization of viral mRNA structures and noncoding RNAs that have led to important insights into the molecular mechanisms of eukaryotic cells. |
format | Online Article Text |
id | pubmed-7127818 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2009 |
publisher | Elsevier Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-71278182020-04-08 Viral RNAs: Lessons from the Enemy Cullen, Bryan R. Cell Article Viruses are adept at evolving or co-opting genomic elements that allow them to maximize their replication potential in the infected host. This evolutionary plasticity makes viruses an invaluable system to identify new mechanisms used not only by viruses but also by vertebrate cells to modulate gene expression. Here, I discuss the identification and characterization of viral mRNA structures and noncoding RNAs that have led to important insights into the molecular mechanisms of eukaryotic cells. Elsevier Inc. 2009-02-20 2009-02-21 /pmc/articles/PMC7127818/ /pubmed/19239880 http://dx.doi.org/10.1016/j.cell.2009.01.048 Text en Copyright © 2009 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article Cullen, Bryan R. Viral RNAs: Lessons from the Enemy |
title | Viral RNAs: Lessons from the Enemy |
title_full | Viral RNAs: Lessons from the Enemy |
title_fullStr | Viral RNAs: Lessons from the Enemy |
title_full_unstemmed | Viral RNAs: Lessons from the Enemy |
title_short | Viral RNAs: Lessons from the Enemy |
title_sort | viral rnas: lessons from the enemy |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7127818/ https://www.ncbi.nlm.nih.gov/pubmed/19239880 http://dx.doi.org/10.1016/j.cell.2009.01.048 |
work_keys_str_mv | AT cullenbryanr viralrnaslessonsfromtheenemy |