Viral RNAs: Lessons from the Enemy

Viruses are adept at evolving or co-opting genomic elements that allow them to maximize their replication potential in the infected host. This evolutionary plasticity makes viruses an invaluable system to identify new mechanisms used not only by viruses but also by vertebrate cells to modulate gene...

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Detalles Bibliográficos
Autor principal: Cullen, Bryan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7127818/
https://www.ncbi.nlm.nih.gov/pubmed/19239880
http://dx.doi.org/10.1016/j.cell.2009.01.048
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author Cullen, Bryan R.
author_facet Cullen, Bryan R.
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description Viruses are adept at evolving or co-opting genomic elements that allow them to maximize their replication potential in the infected host. This evolutionary plasticity makes viruses an invaluable system to identify new mechanisms used not only by viruses but also by vertebrate cells to modulate gene expression. Here, I discuss the identification and characterization of viral mRNA structures and noncoding RNAs that have led to important insights into the molecular mechanisms of eukaryotic cells.
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spelling pubmed-71278182020-04-08 Viral RNAs: Lessons from the Enemy Cullen, Bryan R. Cell Article Viruses are adept at evolving or co-opting genomic elements that allow them to maximize their replication potential in the infected host. This evolutionary plasticity makes viruses an invaluable system to identify new mechanisms used not only by viruses but also by vertebrate cells to modulate gene expression. Here, I discuss the identification and characterization of viral mRNA structures and noncoding RNAs that have led to important insights into the molecular mechanisms of eukaryotic cells. Elsevier Inc. 2009-02-20 2009-02-21 /pmc/articles/PMC7127818/ /pubmed/19239880 http://dx.doi.org/10.1016/j.cell.2009.01.048 Text en Copyright © 2009 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Cullen, Bryan R.
Viral RNAs: Lessons from the Enemy
title Viral RNAs: Lessons from the Enemy
title_full Viral RNAs: Lessons from the Enemy
title_fullStr Viral RNAs: Lessons from the Enemy
title_full_unstemmed Viral RNAs: Lessons from the Enemy
title_short Viral RNAs: Lessons from the Enemy
title_sort viral rnas: lessons from the enemy
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7127818/
https://www.ncbi.nlm.nih.gov/pubmed/19239880
http://dx.doi.org/10.1016/j.cell.2009.01.048
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