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Amino acid substitutions and an insertion in the spike glycoprotein extend the host range of the murine coronavirus MHV-A59

The murine coronavirus [murine hepatitis virus (MHV)] is limited to infection of susceptible mice and murine cell lines by the specificity of the spike glycoprotein (S) for its receptor, murine carcinoembryonic antigen cell adhesion molecule 1a (mCEACAM1a). We have recently shown that 21 aa substitu...

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Detalles Bibliográficos
Autores principales: Thackray, Larissa B, Holmes, Kathryn V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Inc. 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7127820/
https://www.ncbi.nlm.nih.gov/pubmed/15207636
http://dx.doi.org/10.1016/j.virol.2004.04.005