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New prodrugs of Adefovir and Cidofovir

New Adefovir (PMEA) prodrugs with a pro-moiety consisting of decyl or decyloxyethyl chain bearing hydroxyl function(s), hexaethyleneglycol or a (5-methyl-2-oxo-1,3-dioxolen-4-yl)methyl unit were prepared starting from the tetrabutylammonium salt of the phosphonate drug and an appropriate alkyl bromi...

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Detalles Bibliográficos
Autores principales: Tichý, Tomáš, Andrei, Graciela, Dračínský, Martin, Holý, Antonín, Balzarini, Jan, Snoeck, Robert, Krečmerová, Marcela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7127853/
https://www.ncbi.nlm.nih.gov/pubmed/21565516
http://dx.doi.org/10.1016/j.bmc.2011.04.016