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Overexpression of Progerin Results in Impaired Proliferation and Invasion of Non-Small Cell Lung Cancer Cells

PURPOSE: The accumulation of progerin (PG) in patients is responsible for the pathogenesis of Hutchinson-Gilford Progeria Syndrome (HGPS) because it triggers accelerated aging of cells. However, there are few studies on the effects of progerin on tumor cells. Lung cancer is one of the most common ma...

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Detalles Bibliográficos
Autores principales: Hu, Xiao-Ting, Song, Hao-Chang, Yu, Hui, Wu, Zu-Chun, Liu, Xin-Guang, Chen, Wei-Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7127879/
https://www.ncbi.nlm.nih.gov/pubmed/32280239
http://dx.doi.org/10.2147/OTT.S237016