ADAR1 Alleviates Inflammation in a Murine Sepsis Model via the ADAR1-miR-30a-SOCS3 Axis

Adenosine deaminase acting on double-stranded RNA 1 (ADAR1) mediates adenosine-to-inosine (A-to-I) RNA editing events. ADAR1 is highly expressed in “septic” macrophages and in small intestinal tissues of mice with sepsis. Overexpression of ADAR1 suppresses inflammation and intestinal damage. However...

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Detalles Bibliográficos
Autores principales: Shangxun, Zhou, Junjie, Li, Wei, Zhao, Yutong, Wang, Wenyuan, Jia, Shanshou, Liu, Yanjun, Wang, Qianmei, Wang, Zhusheng, Feng, Chaoping, Yu, Ran, Zhuang, Wen, Yin, Yang, Huang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7128072/
https://www.ncbi.nlm.nih.gov/pubmed/32273831
http://dx.doi.org/10.1155/2020/9607535

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7128072/
https://www.ncbi.nlm.nih.gov/pubmed/32273831
http://dx.doi.org/10.1155/2020/9607535

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