Cargando…

ADAR1 Alleviates Inflammation in a Murine Sepsis Model via the ADAR1-miR-30a-SOCS3 Axis

Adenosine deaminase acting on double-stranded RNA 1 (ADAR1) mediates adenosine-to-inosine (A-to-I) RNA editing events. ADAR1 is highly expressed in “septic” macrophages and in small intestinal tissues of mice with sepsis. Overexpression of ADAR1 suppresses inflammation and intestinal damage. However...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shangxun, Zhou, Junjie, Li, Wei, Zhao, Yutong, Wang, Wenyuan, Jia, Shanshou, Liu, Yanjun, Wang, Qianmei, Wang, Zhusheng, Feng, Chaoping, Yu, Ran, Zhuang, Wen, Yin, Yang, Huang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7128072/ https://www.ncbi.nlm.nih.gov/pubmed/32273831 http://dx.doi.org/10.1155/2020/9607535

Ejemplares similares

The ADAR1 editome reveals drivers of editing-specificity for ADAR1-isoforms
por: Kleinova, Renata, et al.
Publicado: (2023)

The ADAR protein family
por: Savva, Yiannis A, et al.
Publicado: (2012)

ADAR1 restricts LINE-1 retrotransposition
por: Orecchini, Elisa, et al.
Publicado: (2017)

Functional conservation in human and Drosophila of Metazoan ADAR2 involved in RNA editing: loss of ADAR1 in insects
por: Keegan, Liam P., et al.
Publicado: (2011)

Optimal guideRNAs for re-directing deaminase activity of hADAR1 and hADAR2 in trans
por: Schneider, Marius F., et al.
Publicado: (2014)

RNA Editing, ADAR1, and the Innate Immune Response
por: Wang, Qingde, et al.
Publicado: (2017)

ADAR1-mediated regulation of melanoma invasion
por: Nemlich, Yael, et al.
Publicado: (2018)

ADAR1 Editing and its Role in Cancer
por: Xu, Li-Di, et al.
Publicado: (2018)

ADAR1 is essential for intestinal homeostasis and stem cell maintenance
por: Qiu, W, et al.
Publicado: (2013)

ADAR1 overexpression is associated with cervical cancer progression and angiogenesis
por: Chen, Ying, et al.
Publicado: (2017)

ADAR1-Mediated RNA Editing and Its Role in Cancer
por: Liu, Jizhe, et al.
Publicado: (2022)

ADAR1- and ADAR2-mediated regulation of maturation and targeting of miR-376b to modulate GABA neurotransmitter catabolism
por: Widmark, Albin, et al.
Publicado: (2022)

ADAR1: “Editor-in-Chief” of Cytoplasmic Innate Immunity
por: Lamers, Mart M., et al.
Publicado: (2019)

ADAR1: a mast regulator of aging and immunity
por: Zhang, Yigan, et al.
Publicado: (2023)

RNA editing enzyme ADAR1 is required for early T cell development
por: Xufeng, Richard, et al.
Publicado: (2020)

Promoting RNA editing by ADAR attraction
por: Danan-Gotthold, Miri, et al.
Publicado: (2017)

ADAR RNA editing below the backbone
por: Keegan, Liam, et al.
Publicado: (2017)

Eight Novel Mutations of the ADAR1 Gene in Chinese Patients with Dyschromatosis Symmetrica Hereditaria
por: Tang, Zhuang-li, et al.
Publicado: (2018)

Modulation of ADAR1 editing activity by Z-RNA in vitro
por: Koeris, Michael, et al.
Publicado: (2005)

ADAR1 is essential for maintenance of hematopoiesis and suppression of interferon signaling
por: Hartner, Jochen C., et al.
Publicado: (2008)

ADAR1 and MicroRNA; A Hidden Crosstalk in Cancer
por: Cho, Charles J., et al.
Publicado: (2017)

Deciphering the Biological Significance of ADAR1–Z-RNA Interactions
por: Nakahama, Taisuke, et al.
Publicado: (2021)

ZBP1 contributes to interferonopathies caused by impaired ADAR1 function
por: Fang, Xiuwu, et al.
Publicado: (2022)

ADAR1-mediated RNA editing promotes B cell lymphomagenesis
por: Pecori, Riccardo, et al.
Publicado: (2023)

A rADAR defense against RNAi
por: Pasquinelli, Amy E.
Publicado: (2018)

Adar3 Is Involved in Learning and Memory in Mice
por: Mladenova, Dessislava, et al.
Publicado: (2018)

ADAR Editing in Viruses: An Evolutionary Force to Reckon with
por: Piontkivska, Helen, et al.
Publicado: (2021)

Five novel mutations in the ADAR1 gene associated with dyschromatosis symmetrica hereditaria
por: Liu, Qi, et al.
Publicado: (2014)

Bioinformatics Analysis Identifies TNFRSF1A as a Biomarker of Liver Injury in Sepsis TNFRSF1A is a Biomarker for Septic Liver Injury
por: Zhou, Shangxun, et al.
Publicado: (2022)

Functions of the RNA Editing Enzyme ADAR1 and Their Relevance to Human Diseases
por: Song, Chunzi, et al.
Publicado: (2016)

ADAR1-mediated RNA-editing of 3′UTRs in breast cancer
por: Sagredo, Eduardo A., et al.
Publicado: (2018)

RNA editing enzyme ADAR1 is required for early T cell development
Publicado: (2022)

The RNA editing enzyme ADAR2 restricts L1 mobility
por: Frassinelli, Loredana, et al.
Publicado: (2021)

ADAR1 Facilitates HIV-1 Replication in Primary CD4(+) T Cells
por: Cuadrado, Eloy, et al.
Publicado: (2015)

ADAR1 averts fatal type I interferon induction by ZBP1
por: Jiao, Huipeng, et al.
Publicado: (2022)

Applying Human ADAR1p110 and ADAR1p150 for Site-Directed RNA Editing—G/C Substitution Stabilizes GuideRNAs against Editing
por: Heep, Madeleine, et al.
Publicado: (2017)

ADAR Regulates RNA Editing, Transcript Stability, and Gene Expression
por: Wang, Isabel X., et al.
Publicado: (2013)

p150 ADAR1 isoform involved in maintenance of HeLa cell proliferation
por: Wang, Haifang, et al.
Publicado: (2006)

Predicting sites of ADAR editing in double-stranded RNA
por: Eggington, Julie M., et al.
Publicado: (2011)

ADAR mediates differential expression of polycistronic microRNAs
por: Chawla, Geetanjali, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_dbnj0c6p3jjnbve71m3gkr4e68