Cross-Regulation of Two Type I Interferon Signaling Pathways in Plasmacytoid Dendritic Cells Controls Anti-malaria Immunity and Host Mortality

Type I interferon (IFN) is critical for controlling pathogen infection; however, its regulatory mechanisms in plasmacytoid cells (pDCs) still remain unclear. Here, we have shown that nucleic acid sensors cGAS-, STING-, MDA5-, MAVS-, or transcription factor IRF3-deficient mice produced high amounts o...

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Detalles Bibliográficos
Autores principales: Yu, Xiao, Cai, Baowei, Wang, Mingjun, Tan, Peng, Ding, Xilai, Wu, Jian, Li, Jian, Li, Qingtian, Liu, Pinghua, Xing, Changsheng, Wang, Helen Y., Su, Xin-zhuan, Wang, Rong-Fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7128466/
https://www.ncbi.nlm.nih.gov/pubmed/27793594
http://dx.doi.org/10.1016/j.immuni.2016.10.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7128466/
https://www.ncbi.nlm.nih.gov/pubmed/27793594
http://dx.doi.org/10.1016/j.immuni.2016.10.001

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