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Structural and molecular modelling studies reveal a new mechanism of action of chloroquine and hydroxychloroquine against SARS-CoV-2 infection

The recent emergence of the novel pathogenic SARS-coronavirus 2 (SARS-CoV-2) is responsible for a worldwide pandemic. Given the global health emergency, drug repositioning is the most reliable option to design an efficient therapy for infected patients without delay. The first step of the viral repl...

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Detalles Bibliográficos
Autores principales: Fantini, Jacques, Di Scala, Coralie, Chahinian, Henri, Yahi, Nouara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. and International Society of Chemotherapy. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7128678/
https://www.ncbi.nlm.nih.gov/pubmed/32251731
http://dx.doi.org/10.1016/j.ijantimicag.2020.105960