Interfering with disease: opportunities and roadblocks to harnessing RNA interference

RNA interference (RNAi) is an evolutionarily conserved mechanism for silencing gene expression by targeted degradation of mRNA. Short double-stranded RNAs, known as small interfering RNAs (siRNA), are incorporated into an RNA-induced silencing complex that directs degradation of RNA containing a hom...

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Detalles Bibliográficos
Autores principales: Lieberman, Judy, Song, Erwei, Lee, Sang-Kyung, Shankar, Premlata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Ltd. 2003
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7128953/
https://www.ncbi.nlm.nih.gov/pubmed/13129706
http://dx.doi.org/10.1016/S1471-4914(03)00143-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7128953/
https://www.ncbi.nlm.nih.gov/pubmed/13129706
http://dx.doi.org/10.1016/S1471-4914(03)00143-6

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