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Immune regulation and cytotoxic T cell activation of IL-10 agonists – Preclinical and clinical experience

The expansion and activation of tumor antigen reactive CD8(+) T cells are primary goals of immunotherapies for cancer. IL-10 is an anti-inflammatory cytokine with an essential role in the development and proliferation of regulatory T cells, restricting myeloid and chronic inflammatory T cell respons...

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Detalles Bibliográficos
Autor principal: Oft, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7129358/
https://www.ncbi.nlm.nih.gov/pubmed/31706853
http://dx.doi.org/10.1016/j.smim.2019.101325