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Immune regulation and cytotoxic T cell activation of IL-10 agonists – Preclinical and clinical experience
The expansion and activation of tumor antigen reactive CD8(+) T cells are primary goals of immunotherapies for cancer. IL-10 is an anti-inflammatory cytokine with an essential role in the development and proliferation of regulatory T cells, restricting myeloid and chronic inflammatory T cell respons...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier Ltd.
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7129358/ https://www.ncbi.nlm.nih.gov/pubmed/31706853 http://dx.doi.org/10.1016/j.smim.2019.101325 |