Template-based coiled-coil antigens elicit neutralizing antibodies to the SARS-coronavirus

The Spike (S) glycoprotein of coronaviruses (CoV) mediates viral entry into host cells. It contains two hydrophobic heptad repeat (HR) regions, denoted HRN and HRC, which oligomerize the S glycoprotein into a trimer in the native state and when activated collapse into a six-helix bundle structure dr...

Descripción completa

Detalles Bibliográficos
Autores principales: Tripet, Brian, Kao, Daniel J., Jeffers, Scott A., Holmes, Kathryn V., Hodges, Robert S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2006
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7129695/
https://www.ncbi.nlm.nih.gov/pubmed/16697221
http://dx.doi.org/10.1016/j.jsb.2006.03.019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7129695/
https://www.ncbi.nlm.nih.gov/pubmed/16697221
http://dx.doi.org/10.1016/j.jsb.2006.03.019

Ejemplares similares