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A Novel Therapeutic and Prophylactic Vaccine against Tuberculosis Using the Cynomolgus Monkey Model and Mouse Model

We have developed a novel tuberculosis (TB) vaccine; a combination of the DNA vaccines expressing mycobacterial heat shock protein 65 (HSP65) and interleukin 12 (IL-12) delivered by the hemagglutinating virus of Japan (HVJ)-envelope and –liposome (HSP65 + IL-12/HVJ). This vaccine provided remarkable...

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Detalles Bibliográficos
Autores principales: Okada, M., Kita, Y., Nakajima, T., Kanamaru, N., Kaneda, Y., Saunderson, P., Tan, E.V., McMurray, DN.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier B.V. 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7129750/
https://www.ncbi.nlm.nih.gov/pubmed/32288912
http://dx.doi.org/10.1016/j.provac.2011.07.007