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A Novel Therapeutic and Prophylactic Vaccine against Tuberculosis Using the Cynomolgus Monkey Model and Mouse Model
We have developed a novel tuberculosis (TB) vaccine; a combination of the DNA vaccines expressing mycobacterial heat shock protein 65 (HSP65) and interleukin 12 (IL-12) delivered by the hemagglutinating virus of Japan (HVJ)-envelope and –liposome (HSP65 + IL-12/HVJ). This vaccine provided remarkable...
Autores principales: | Okada, M., Kita, Y., Nakajima, T., Kanamaru, N., Kaneda, Y., Saunderson, P., Tan, E.V., McMurray, DN. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Published by Elsevier B.V.
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7129750/ https://www.ncbi.nlm.nih.gov/pubmed/32288912 http://dx.doi.org/10.1016/j.provac.2011.07.007 |
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