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Poliovirus RNA Replication Requires Genome Circularization through a Protein–Protein Bridge

The mechanisms and factors involved in the replication of positive stranded RNA viruses are still unclear. Using poliovirus as a model, we show that a long-range interaction between ribonucleoprotein (RNP) complexes formed at the ends of the viral genome is necessary for RNA replication. Initiation...

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Detalles Bibliográficos
Autores principales: Herold, Jens, Andino, Raul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press. 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7129834/
https://www.ncbi.nlm.nih.gov/pubmed/11463383
http://dx.doi.org/10.1016/S1097-2765(01)00205-2