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Intranasal administration of IL-35 inhibits allergic responses and symptoms in mice with allergic rhinitis
BACKGROUND: IL-35 was recently identified as an anti-inflammatory cytokine. We previously reported that recombinant fusion protein of murine IL-35 and human IgG1 Fc fragment (rIL-35) reduced Th2 cytokines (IL-4 and IL-5) in vitro. However, it is unclear whether IL-35 can attenuate nasal allergic res...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
, Japanese Society of Allergology. Production and hosting by Elsevier B.V.
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7130026/ https://www.ncbi.nlm.nih.gov/pubmed/27707583 http://dx.doi.org/10.1016/j.alit.2016.08.014 |