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The Murray Valley encephalitis virus prM protein confers acid resistance to virus particles and alters the expression of epitopes within the R2 domain of E glycoprotein

To study the role of the precursor to the membrane protein (prM) in flavivirus maturation, we inhibited the proteolytic processing of the Murray Valley encephalitis (MVE) virus prM to membrane protein in infected cells by adding the acidotropic agent ammonium chloride late in the virus replication c...

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Detalles Bibliográficos
Autores principales: Guirakhoo, Farshad, Bolin, Richard A., Roehrig, John T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Inc. 1992
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7130970/
https://www.ncbi.nlm.nih.gov/pubmed/1280384
http://dx.doi.org/10.1016/0042-6822(92)90267-S