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Evaluation of the genotoxicity potential and chronic inhalation toxicity of 1,1-dichloro-1-fluoroethane (HCFC-141 b)()()

A battery of in vitro and in vivo tests were conducted on HCFC-141b as a vapour. Bacterial gene mutation assays with Escherichia coli and Salmonella typhimurium were negative in all tester strains. In vitro chromosomal aberration assays were positive on CHO cells but negative on human lymphocytes. M...

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Detalles Bibliográficos
Autores principales: Millischer, R.-J., de Rooij, C.G., Rush, G.M., Farr, C.H., Ben-Dyke, R., Hardy, C.J., Lewis, D.J., Hodson-Walker, G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Ltd. 1995
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7131127/
https://www.ncbi.nlm.nih.gov/pubmed/7797176
http://dx.doi.org/10.1016/0278-6915(95)00015-T