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Evaluation of the genotoxicity potential and chronic inhalation toxicity of 1,1-dichloro-1-fluoroethane (HCFC-141 b)()()
A battery of in vitro and in vivo tests were conducted on HCFC-141b as a vapour. Bacterial gene mutation assays with Escherichia coli and Salmonella typhimurium were negative in all tester strains. In vitro chromosomal aberration assays were positive on CHO cells but negative on human lymphocytes. M...
Autores principales: | Millischer, R.-J., de Rooij, C.G., Rush, G.M., Farr, C.H., Ben-Dyke, R., Hardy, C.J., Lewis, D.J., Hodson-Walker, G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Published by Elsevier Ltd.
1995
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7131127/ https://www.ncbi.nlm.nih.gov/pubmed/7797176 http://dx.doi.org/10.1016/0278-6915(95)00015-T |
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