Cargando…

Reduced mouse neurovirulence of poliovirus type 2 lansing antigenic variants selected with monoclonal antibodies

The Lansing strain of poliovirus type 2 is a mouse-adapted virus that induces a fatal paralytic disease in mice after intracerebral inoculation. Our previous results indicated that the mouse-adapted phenotype maps to the Lansing viral capsid. To further define regions of the capsid that are specific...

Descripción completa

Detalles Bibliográficos
Autores principales: La Monica, Nicola, Klipsky, William J., Racaniello, Vincent R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Inc. 1987
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7131194/
https://www.ncbi.nlm.nih.gov/pubmed/2825415
http://dx.doi.org/10.1016/0042-6822(87)90136-X