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Reduced mouse neurovirulence of poliovirus type 2 lansing antigenic variants selected with monoclonal antibodies
The Lansing strain of poliovirus type 2 is a mouse-adapted virus that induces a fatal paralytic disease in mice after intracerebral inoculation. Our previous results indicated that the mouse-adapted phenotype maps to the Lansing viral capsid. To further define regions of the capsid that are specific...
Autores principales: | La Monica, Nicola, Klipsky, William J., Racaniello, Vincent R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Published by Elsevier Inc.
1987
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7131194/ https://www.ncbi.nlm.nih.gov/pubmed/2825415 http://dx.doi.org/10.1016/0042-6822(87)90136-X |
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