Sequence analysis of the spike protein gene of murine coronavirus variants: Study of genetic sites affecting neuropathogenicity

Mouse hepatitis virus (MHV), a coronavirus, causes encephalitis and demyelination in susceptible rodents. Previous investigations have shown that the MHV spike (S) protein is a critical determinant of viral tropism and pathogenicity in mice and rats. To understand the molecular basis of MHV neuropat...

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Detalles Bibliográficos
Autores principales: Wang, F.-I., Fleming, John O., Lai, Michael M.C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Inc. 1992
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7131202/
https://www.ncbi.nlm.nih.gov/pubmed/1310195
http://dx.doi.org/10.1016/0042-6822(92)90041-M

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7131202/
https://www.ncbi.nlm.nih.gov/pubmed/1310195
http://dx.doi.org/10.1016/0042-6822(92)90041-M

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