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A single point mutation of the influenza C virus glycoprotein (HEF) changes the viral receptor-binding activity
From strain JHB/1/66 of influenza C virus a mutant was derived with a change in the cell tropism. The mutant was able to grow in a subline of Madin-Darby canine kidney cells (MDCK II) which is resistant to infection by the parent virus due to a lack of receptors. Inactivation of cellular receptors b...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Published by Elsevier Inc.
1992
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7131248/ https://www.ncbi.nlm.nih.gov/pubmed/1566586 http://dx.doi.org/10.1016/0042-6822(92)90737-A |