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A single point mutation of the influenza C virus glycoprotein (HEF) changes the viral receptor-binding activity

From strain JHB/1/66 of influenza C virus a mutant was derived with a change in the cell tropism. The mutant was able to grow in a subline of Madin-Darby canine kidney cells (MDCK II) which is resistant to infection by the parent virus due to a lack of receptors. Inactivation of cellular receptors b...

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Detalles Bibliográficos
Autores principales: Szepanski, Sigrun, Gross, H.J., Brossmer, R., Klenk, H.-D., Herrler, G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Inc. 1992
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7131248/
https://www.ncbi.nlm.nih.gov/pubmed/1566586
http://dx.doi.org/10.1016/0042-6822(92)90737-A