Expression of Interferon-γ by a Coronavirus Defective-Interfering RNA Vector and Its Effect on Viral Replication, Spread, and Pathogenicity

A defective-interfering (DI) RNA of the murine coronavirus mouse hepatitis virus (MHV) was developed as a vector for expressing interferon-γ (IFN-γ). The murine IFN-γ gene was cloned into the DI vector under the control of an MHV transcriptional promoter and transfected into MHV-infected cells. IFN-...

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Detalles Bibliográficos
Autores principales: Zhang, Xuming, Hinton, David R., Cua, Daniel J., Stohlman, Stephen A., Lai, Michael M.C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press. 1997
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7131250/
https://www.ncbi.nlm.nih.gov/pubmed/9217056
http://dx.doi.org/10.1006/viro.1997.8598

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7131250/
https://www.ncbi.nlm.nih.gov/pubmed/9217056
http://dx.doi.org/10.1006/viro.1997.8598

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