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Characterisation and Mutational Analysis of an ORF 1a-Encoding Proteinase Domain Responsible for Proteolytic Processing of the Infectious Bronchitis Virus 1a/1b Polyprotein

Coronavirus gene expression involves proteolytic processing of the mRNA 1-encoded polyproteins by viral and cellular proteinases. Recently, we have demonstrated that an ORF 1b-encoded 100-kDa protein is proteolytically cleaved from the 1a/1b fusion polyprotein by a viral-specific proteinase of the p...

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Detalles Bibliográficos
Autores principales: Liu, D.X., Brown, T.D.K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press. 1995
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7131408/
https://www.ncbi.nlm.nih.gov/pubmed/7778277
http://dx.doi.org/10.1006/viro.1995.1274