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Localization of Neurovirulence Determinant for Rats on the S1 Subunit of Murine Coronavirus JHMV

A cloned virus of murine coronavirus JHMV, cl-2, was shown to be highly neurovirulent for rats in comparison with other JHMV variants. We have isolated cl-2-derived variant viruses resistant to neutralization by monoclonal antibodies (MAbs) specific for the spike (S) protein of cl-2. The variants MM...

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Detalles Bibliográficos
Autores principales: Taguchi, Fumihiro, Kubo, Hideyuki, Takahashi, Hiromi, Suzuki, Hideka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press. 1995
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7131550/
https://www.ncbi.nlm.nih.gov/pubmed/11831732
http://dx.doi.org/10.1006/viro.1995.1130