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Selection of and evasion from cytotoxic T cell responses in the central nervous system

Cytotoxic CD8 T lymphocytes (CTLs) are critical for the clearance of noncytopathic viruses from infected cells. This chapter discusses one mechanism used by viruses to persist—namely, the selection of a variant virus in which changes in the sequence of a CTL epitope abrogate recognition. The unique...

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Detalles Bibliográficos
Autores principales: Perlman, Stanley, Wu, Gregory F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Inc. 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7131566/
https://www.ncbi.nlm.nih.gov/pubmed/11450301
http://dx.doi.org/10.1016/S0065-3527(01)56029-7