Altered Pathogenesis of a Mutant of the Murine Coronavirus MHV-A59 Is Associated with a Q159L Amino Acid Substitution in the Spike Protein()

C12, an attenuated, fusion delayed, very weakly hepatotropic mutant of mouse hepatitis virus strain A59 (MHV-A59) has been further characterized. We have previously shown that C12 has two amino acid substitutions relative to wild type virus in the spike protein, Q159L (within a region of S1 shown to...

Descripción completa

Detalles Bibliográficos
Autores principales: Leparc-Goffart, Isabelle, Hingley, Susan T., Chua, Ming Ming, Jiang, Xinhe, Lavi, Ehud, Weiss, Susan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press. 1997
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7131600/
https://www.ncbi.nlm.nih.gov/pubmed/9426441
http://dx.doi.org/10.1006/viro.1997.8877

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7131600/
https://www.ncbi.nlm.nih.gov/pubmed/9426441
http://dx.doi.org/10.1006/viro.1997.8877

Ejemplares similares